| Dihydroberberine | |||
| Product Code | N/A | Specification | Dihydroberberine 98% |
| Extract Solvent | Ethanol / Water | Assay Method | HPLC |
| CAS NO. | 483-15-8 | Molecular Formula | C20H19NO4 |
| EINECS No. | N/A | Molecular Weight | 337.37 |
| Character | Light Yellow | Certification | ISO22000 |
| HS Code | 3006930000 | Shelf Life | 2 Years |

DHB exerts its uric acid-lowering effect by inhibiting the activation of XOD, URAT1, GLUT9, and NLRP3 inflammatory vesicles in the kidneys, and is renoprotective in addition to being antihyperuricemic.
The treatment of DHB had a protective effect on renal function.
These results suggest that DHB ameliorates renal injury and has a nephroprotective effect in HUA mice.
DHB showed XOD enzyme inhibition in a concentration-dependent manner.DHB significantly inhibited XOD activity (Figure 4D). This result suggests that DHB has an inhibitory effect on XOD.
Treatment with DHB was effective in ameliorating PO/HX-induced renal inflammation.
DHB showed the ability to inhibit XOD activity both in vitro and in vivo.
And the treatment of DHB also showed significant inhibition of renal URAT1 and GLUT9 levels.
Thus, DHB was able to reduce urate formation by inhibiting hepatic XOD while down-regulating renal URAT1 and GLUT9 to enhance urate excretion, suggesting a dual anti-hyperuricemic effect.
In addition, the mechanism by which DHB exerts its renoprotective effects was found to be through the inhibition of NLRP3 inflammasome activation to attenuate renal inflammation and dysfunction.
FAQ
Q1: What's the difference between herb extract and powder?
A: The extract is a concentrated powder form of raw material. The herb extract's procedure flow is wash, extraction, concentration, purification, drying, grinding, sieving, package. The herb powder is just a powder form of the herb. The procedure flow is wash, drying, grinding, sieving, package.
Q2: What's the extract solvent used in the procedure?
A: The extract solvent is always depending on the active ingredient in the raw material, regulation and customers' requirement. The solvents mostly used for extraction are water and ethanol. Even the solvent other than water used in the procedure, the solvent residue in the extract product also can conform with ICH Q3CR5.
Q3: Is there any other ingredient used in the product?
A: It depends. For product which is hard to be dried, we need to add some maltodextrin into the extraction solution before drying. The maltodextrin we used is food-class carrier, from non-GMO corn. We can share customer with the ingredient composition table.
Q4: How to make sure the quality of the product?
A: Firstly, every batch finish product must be tested and qualified before delivery. We can send a specification sheet or CoA for confirmation. The HPLC chromatography graph also can be provided. Secondly, we can provide pre-ship sample to customer for quality confirmation.
Q5: Can you develop a new product for us?
A: Yes, we can. We have independent R&D dept, who is able to update the procedure parameters of our main products and develop the procedure of new product. For more information, please contact us directly.
Q6: Can you offer this in capsules or tablets as well?
A: Yes, we have related equipment for preparation of finish product, like tablet, capsule and granule. Kindly contact with us for details.
Q7: What is the MOQ?
A: For most of the products we already have in stock, the MOQ is 1kg. If the product is a new specification and need to be produced from raw material, the MOQ depends.
Q8: Is there any discount?
A: Yes, for larger quantity or better payment period, we can support with better price.
Q9: How about delivery time?
A: For most products, the product can be sent out from factory in 5days. If we don't have inventory, the product need to produced from raw material, the ordinary period is 20-25days.
Q10: How do you treat with quality complaint?
A: We will always be responsible for the quality of our products. If there's a complaint, we will first assist customers to solve the most direct needs.
Secondly, we have SOP for quality complaint. QA will investigate the problem, after that we'll give customer a formal feedback about the cause of the quality issue and related precautions for this problem.
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|---|---|---|
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5,7-Dimethoxyflavone: 1-20% |
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| Black Garlic Extract | SAC 0.1-4%; Polyphenol 1-3% | |
| Rhodiola Rosea Extract | Rosavins 3%-5%, Rhodioside 1-2% | |
| Ginkgo Biloba Extract | USP42/EP10.0/CP2020, water soluble available | |
| Mulberry Leaf Extract | Rutin>0. 1%; Total Flavone >0. 1-3%; DNJ 0.8%/HPLC; DNJ 1%/HPLC | |
| Saffron Extract | Safranal 0.3% | |
| Sakura Extract | 1- O-caaffeyl -β -d-glucopyranoside 2%, Quercetin -3-O-β -D-glucopyranoside 0.1% | |
| Schisandra Berry Extract | Schisandrins 2-10%; Schisandrin A 1-4%; Schisandrin B 0.5-2% | |
| Ginseng Series | American Ginseng Extract | Ginsenosides 1-70% HPLC; Ginsenosides 1-70% UV; Polysaccharides 20% |
| Panax Ginseng Extract | Ginsenosides 1-60% HPLC; Ginsenosides 1-80% UV; Polysaccharides 20% | |
| Black Ginseng Extract | Ginsenosides 1-60% HPLC; Ginsenosides 1-80% UV; Polysaccharides 20% | |
| CLEAN-GINSENG® | Ginsenosides 4% HPLC, Solubility (20℃): ++ | |
| Korean Red Ginseng Extract | Ginsenosides 1-60% HPLC; 1-60% UV | |
| Notoginseng (Tienchi) Extract | Ginsenosides 1-80% HPLC | |
| Siberian Ginseng Extract | Total rare ginsenosides>20% HPLC (Rk2+ (S)-Rg3+ (R)-Rg3+ (S)-Rh2+ (R)-Rh2+ Rg5+ Rk1+Rk3+ (S)-Rh1+ (R)-Rh1+ Rh3+ Rh4 + (S)-aPPT+ (R)-aPPT+ (S)-aPPD+ (R)-aPPD) |
|
| Rare Ginsenosides | Eleutherosides (B+E) 0.8-1.2% | |
| Mushroom Series | Chaga Mushroom Extract | Polysaccharides 30%; Triterpene 1-10% |
| Lion's Mane Mushroom Extract | β-Glucan 1-10%; Polysaccharides 30% | |
| Reishi Mushroom Extract | β-Glucan 1-10%; Polysaccharides 30%; Triterpene 1-30% | |
| Maitake Mushroom Extract | Polysaccharides 30% | |
| Shiitake Mushroom Extract | Polysaccharides 30% | |
| Cordyceps Militaris Powder | β-Glucan 1-10%; Polysaccharides 30% | |
| Organic Products | Organic Apple Cider Vinegar Powder | Total Acid 5% |
| Organic Blueberry Extract | Ratio Extract | |
| Organic Craneberry Extract | Ratio Extract ; Proanthocyanidin 30% | |
| Organic Elderberry Extract | 25% Polyphenol; Extract Ratio: 4: 1 & 5: 1; Anthocyanins4-30%; Flavone 5%; | |
| Organic Turmeric Extract | Ratio Extract | |
| Fruit Powder | Acai SD Powder | 4:1 |
| Acerola Cherry Extract | VC 16-18%; SD Powder | |
| Aronia Extract | Anthocyanins 5-15%; SD Powder | |
| Black Currant Extract | Anthocyanins 5-35% HPLC; SD Powder | |
| Instant Tea Powder | Organic Matcha Powder | D60 500 Mesh |
| Kombucha | Freeze-dried Powder | |
| TF-Roberts® Black Tea Extract | Theaflavins≥5%, Caffeine≤6% | |
| Instant Tea PowderLion's mane extract | Instant Powder, Polyphenol>20% | |
| L-Theanine | 20-40% HPLC, Nature origin | |










